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Discontinuation rates are higher among lower-income groups, those with multiple health conditions, and patients over 65
Contact your doctor or healthcare team if you experience: Persistent or severe nausea, vomiting, or diarrhoea affecting your ability to eat, drink, or function normally Signs of dehydration from persistent gastrointestinal losses, such as dizziness, light-headedness, or significantly reduced urination Signs of pancreatitis , including severe upper abdominal pain that may radiate to the back call 999 or go to your nearest A&E immediately if pain is severe Gallbladder symptoms such as right upper abdominal pain, fever, or yellowing of the skin or eyes (jaundice) Symptoms of hypoglycaemia (low blood sugar) particularly if you are also taking diabetes medications such as insulin or sulphonylureas
The remaining authors declare no competing financial interests
Ongoing therapy typically includes: Yes, many people eventually taper off
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