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Key takeaways: Glucagon-like peptide-1 (GLP-1) medications like semaglutide (Wegovy, Ozempic, Rybelsus) and tirzepatide (Zepbound, Mounjaro) arent interchangeable
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These include genetic variation (3539), including the hypothesized thrifty and drifty genotypes (4043), the heterogenous presence of an obesogenic environment (4449), developmental abnormalities (5058), diet-induced hypothalamic inflammation (5962), psychological or physiological changes in the rewarding properties of food, and socioeconomic factors (6367)
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In some cases, patients may experience feelings of sadness, anxiety, or a general flatness of mood
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