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Although these compounds displayed lower activity than conventional drugs like Vildagliptin and Sitagliptin, two of the newly synthesized compounds showed potential DPP-4 inhibitory effects at a concentration of 10 M
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We advise against the use of these medications for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
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GDF15 induces anorexia through nausea and emesis
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