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In parallel, digital twin platforms that incorporate genomic, metabolic, and behavioral data are being developed to simulate individualized pharmacokinetics and support evidence-based therapy selection and adjustment [466, 467]

Thomas M, Harjutsalo V, Feodoroff M et al (2020) The long-term incidence of hospitalization for ketoacidosis in adults with established T1D-a prospective cohort study

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In practice, Roche is likely integrating BioNeMo with its internal chemical databases, assay results, and high-throughput screening data to automate hypothesis generation