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Large doses of folic acid given to an individual with an undiagnosed vitamin B 12 deficiency can correct megaloblastic anemia without correcting the underlying vitamin B 12 deficiency, leaving the individual at risk of developing irreversible neurologic damage (21)

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Also cannot eat, drink (including water) or smoke anything for a minimum of 2 hours prior to testing

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A published case series on cobalamin disorders described subcutaneous B12 as a gentle, easy-to-use alternative to intramuscular injections