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+++ represent significance compared to other positive drug (++)
B12 (hydroxocobalamin) is a prescription-only medicine in the UK and is safest given by, or under the supervision of, a trained clinician
Deficiency of vitamin B-12 can lead to neurological difficulties and anaemia
We may speculate that a larger reduction of plasma aldosterone in the patients with advanced CKD seen in our study could be caused by a higher local activity of RAAS due to kidney dysfunction
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