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Purpose-built for physicians GLP-1s may reduce steroid dependence, hospitalizations in patients with Crohns, obesity Key takeaways: Patients with Crohns disease and overweight or obesity who used GLP-1s appeared less likely to become steroid dependent or be hospitalized

Over the past several years, we have seen a great deal of enthusiasm about the use of incretin therapies to promote weight loss much larger than those seen with caloric restriction and increased physical activity, he said

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Another aspect of the present invention relates to an anion exchange chromatography process for purifying a GLP-1 peptide from a mixture comprising said peptide and related impurities, comprising the step of: separating said GLP-1 peptide and said related impurities of said mixture by elution in a solution consisting essentially of an organic modifier, water, optionally a salt component, and optionally a buffer, with a linear or step gradient or isocratically in salt component and/or with a linear or step pH-gradient or at a constant pH-value, wherein the pH-gradient or pH-value should be in the range where said peptide has a negative local or overall net charge different from the local or overall negative net charge of said related impurities so as to remove said related impurities

As peptide usage is getting more popular in real time, research is doing its best to keep up with what exactly all those concerns are