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Disproportionality analysis A sequential approach was adopted to systematically address major confounders: (1) An exploratory disproportionality approach comparing GLP-1RAs with all other drugs reported in the FAERS database, using venlafaxine as the positive control and empagliflozin/orlistat as the negative control

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Live cell images were acquired by Confocal Laser Scanning Microscope (CLSM, Leica Microsystem, Germany)