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138 The dose-response trial also lacked a placebo control group and reported at eight months no differences in proportions of patients experiencing clinically significant improvements (300 mg daily 50%

Furthermore, they significantly contribute to maintaining of homeostasis by binding, transport or inactivation of biologically active compounds such as hormones, bile acids, or other mediators

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Nanoparticles can cross membranes, accumulate in organs, and potentially cause tissue damage (Nel et al