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These medications were developed by the monoamine hypothesis, which may be attributed to a deficiency in monoamine neurotransmitters ( Figure 1 illustrates the efficacy of probiotics, particularly butyrate-producing bacteria, to alleviate the physiological causes of MDD while also structurally modulating the intestinal flora

The withanolides present in Ashwagandha may influence monoamine oxidase (MAO) activity, which subsequently enhances the synaptic availability of monoamines

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Ramirez-Guerra, H

8. Long-Term Healthy Aging Support