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Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes
21% of them had polymorphisms and pathogenic/likely pathogenic mutations in the genes ATP8B1, ABCB11, ABCB4, and TJP2
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High cost, side effects, dependence, and lack of behavioral change remain major challenges
This two-pronged approach is clinically shown to produce greater weight loss and more robust metabolic improvements than single-receptor medications
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