AugsteinPNaselliGLoudovarisTHawthorneWJCampbellPBandala-SanchezEet al
Chemotherapy Support: May reduce side effects of chemotherapy
According to reports, curcumin is a P450 inhibitor that inhibits CYP2C9, CYP1A2, CYP2D6, CYP2B6 and CYP3A4, with particularly low IC50 values for CYP2C9 (Sasaki et al., 2017)
282,283 These cells accumulate in the synovial membrane and subchondral bone, releasing pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which promote the degradation of joint cartilage and the inflammatory response
Common side effects may include nausea or fatigue during the first few doses, but these usually subside as your body adjusts