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Preclinical studies in rodents consistently show reduced alcohol intake with GLP-1 medications, but human clinical trials have produced mixed results
International journal of molecular sciences, 24(23), 16588
In a retrospective study of 30 patients with HS treated with semaglutide at an average weekly dose of 0.8 mg, there was a reduction in patient-reported flare-ups and a significant improvement in mean DLQI scores
Lancet Gastroenterol Hepatol
Studies have shown that semaglutide treatment increases populations of Akkermansia muciniphila, a bacteria associated with healthy metabolic function, while decreasing overall microbial diversity
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