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Clinical trials show that people taking tirzepatide eat roughly 25-30% fewer calories without conscious dieting, and this shift happens because food signals feel fundamentally different

Part D will continue to cover the meds for those patients, but the new Medicare GLP-1 Bridge program will expand GLP-1 coverage to certain patients who want to reduce excess body weight or maintain weight reduction

Mild side effects may include temporary soreness at the injection site or mild digestive changes

Conversely, in another phase 2b study involving patients with T2DM, tirzepatide showed significantly better efficacy in glucose control and weight loss compared to both placebo and dulaglutide, with an acceptable safety and tolerability profile (111)

(2020) 34:e8932