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vitamin B12-deficient patients with tobacco amblyopia due to cyanide poisoning

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Patients had undergone laparoscopic sleeve gastrectomy before starting semaglutide

This phenomenon, sometimes called tolerance or tachyphylaxis, is not well-studied specifically for semaglutide, but it is reported frequently in practice

Preclinical models have examined how this fragment influences fat cell mobilization and lipogenesis without measurable impact on insulin-like growth factor-1 (IGF-1) levels, distinguishing it mechanistically from intact growth hormone