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Many classical ferroptosis inducers, such as erastin and RAS-selective lethal 3, can target the xCT/GPX4 axis, and these inducers can trigger ferroptosis in cancer cells, suggesting they hold promise in the treatment of cancer [40, 42]

Mean differences (MD) were used as the summary measure when outcomes were reported using the same unit of measurement across studies, while standardized mean differences (SMD) were applied when outcomes were measured on different scales

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Body weights were measured before treatment and then once a week till sacrificed

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