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Reconstituted BPC-157 in bacteriostatic water begins degrading immediately above 8C

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Altered immune response to exercise in patients with chronic fatigue syndrome/myalgic encephalomyelitis: a systematic literature review

Monitor Your Symptoms and Side Effects Keep track of any new or worsening symptoms during Isotretinoin therapy

This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice