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It impairs insulin sensitivity, increases cortisol production, and reduces the secretion of growth hormone, which plays a critical role in fat oxidation and muscle preservation during sleep

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However, the researchers suggest that additional mechanisms may also be involved

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The guidelines were also published in Pediatrics, an AAP journal, which has its own industry relationships

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For weight management, only semaglutide (Wegovy) and liraglutide (Saxenda) are specifically licensed in the UK, with access typically through specialist weight management services according to NICE criteria

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