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BPC-157 supports tissue repair and gut integrity

They found that a stable GLP-1-estradiol conjugate caused greater weight loss in obese male mice than either GLP-1 controls or labile GLP-1-estradiol conjugates

Puopolo characterized this as evidence that the drugs reach the brain's reward circuitry, with the clearest data so far around alcohol and emerging signals for nicotine, opioids, and compulsive behaviors

One unanswered question is whether long-term use could lead to reduced responsiveness over time

More specifically, the most widely speculated daily dosage for BPC-157 oral capsules is around 250mcg, typically administered 1-3 times daily