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doi: 10.1016/j.gde.2016.02.007 169 VahsenNCandeCBriereJJBenitPJozaNLarochetteNet al
Reconstitution refers to the process of dissolving a lyophilised (freeze-dried) powder into a liquid solution to prepare it for injection
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For weekly GLP-1 medications, the window to take a missed dose varies by product: semaglutide (Ozempic) allows 5 days, semaglutide (Wegovy) allows 2 days, dulaglutide (Trulicity) allows 3 days, and tirzepatide (Mounjaro/Zepbound) allows 4 days
Herein we report a series of GLP-1-oligourea hybrids with moderate to excellent affinity to GLP-1R including three hybrids with prolonged action in mice
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