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Lustig discusses eight pathologies that lead to metabolic dysfunction: Glycation Oxidative Stress Mitochondrial Dysfunction Insulin Resistance Membrane Integrity Inflammation Epigenetics Autophagy Lustig gives his solutions in Part V which rely on government intervention (soda tax, eliminate farm subsidies, ban access to soda in institutions)

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In many cases, these improvements may be significant enough that they can stop taking one or more medications related to these conditions