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They work together to neutralize free radicals

The heterogeneous presentation of symptoms among patients, lack of definitive biomarkers and diagnostic tests, and multitude of differential diagnoses make ALS difficult to diagnose, with the time between symptom onset and diagnosis often exceeding 12 months ( By definition, a biomarker is a medical sign in the body that can be measured accurately and reproducibly and that can influence or predict the incidence of outcome or disease ( Common biomarkers are often proteins or other molecules in blood, urine, and cerebrospinal fluid

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