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Severe, persistent abdominal pain (with or without vomiting), signs of gallstones (right upper abdominal pain, jaundice), or signs of dehydration warrant urgent medical assessment

Previously, it was thought that acetaminophen induces analgesia by inhibiting the enzyme cyclooxygenase (COX), but now it is believed that acetaminophen is metabolized to p -aminophenol, which crosses the blood-brain barrier and gets metabolized by fatty acid amide hydrolase to yield N -acylphenolamine (AM404)

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Dement Geriatr Cognit Disord (2020) 49(5):42334