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TB-500 also exhibits clinically relevant anti-inflammatory properties through downregulation of inflammatory cytokines including TNF- and IL-1
Compounds excreted into bile enter the intestine, but entry into the gut does not guarantee final removal
T-cell antigen specificity arises from T-cell receptors (TCRs), which recognize antigen-derived peptides presented by MHC molecules on APCs (95, 96)
doi: 10.1186/1471-2407-14-941 206 CleggDJBrownLMWoodsSCBenoitSC
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