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178 For example, a cross-sectional study published in 2023 found that, compared with non-users of hormone replacement therapy, initiation of hormone replacement therapy five or more years after menopause was associated with increased tau protein accumulation apparent on brain PET scans, whereas initiation within five years of menopause was not

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However, deciding whether a new treatment is suitable requires looking beyond early results and considering personal health needs, treatment goals and available evidence

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Biomedical Dermatology