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To validate the impact of FOXO4-DRI on the P53 signaling pathway in senescent endothelial cells, Co-IP experiments were performed

The peptide contains an internal disulfide bond between the two cysteine residues, which is critical for its three-dimensional conformation

The maintenance of this mitochondrial GSH pool occurs through the action of a high-affinity GSH uptake system [43] which is a main determinant of neuronal susceptibility to OS [44]

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