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Gclc is required for T cell-independent and -dependent B cell immune responses Next, we aimed to understand how the metabolic perturbations caused by B cell-specific Gclc ablation impinge on immune responses and in particular how the impaired mitochondrial metabolism affects the antibody response

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Appetite Suppression: A consequence of MC4R activation

Here, we could demonstrate that blocking zonulin with the specific antagonist larazotide acetate was sufficient to restore the impaired barrier function in intestinal organoid cultures exposed to complete fecal supernatants from CIA mice containing high zonulin levels

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