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Mice were started on intraperitoneal injection (ip) of copper-free GHK (Peptide Sciences, Henderson, NV ) at a dose of 7.5 mg/kg ( n = 8), or ip saline ( n = 12), twice daily for five days

This is an important distinction between both peptides because Ghrelin is responsible for initiating the breakdown of fat for use as energy as well as preventing the breakdown of muscles

After the completion of the study, it was noted that there appeared to be a significant reduction in the body weight of these murine models, including a reduction of excess body lipids

What is the proposed mechanism of BPC-157

doi: 10.1021/acschembio.0c00968 67 LiJLiYIveyKLWangDDWilkinsonJEFrankeAet al