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In addition, GLP-1/glucagon and GLP-1/GIP dual receptor agonists and GLP-1/GIP/glucagon triple receptor agonists have shown the potential to reduce blood glucose levels and body weight through their effects on islets and peripheral tissues, improving beta cell function and stimulating energy expenditure

65-year-old patient Enalapril + Furosemide Diclofenac added for pain Within days: Urine output dropped Creatinine spiked Diagnosis: This is the ACE inhibitor + Diuretic + NSAID Individually

And the use of DPP-4 inhibitors did not raise the risk of thyroid cancer compared with SGLT2 inhibitors or other treatment alternatives [113, 114]

Talk to your diabetes care team about whether a GLP-1 receptor agonist is appropriate for you approved options already exist