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proton magnetic resonance spectroscopy (MRS) may show decreased peaks of N-acetylaspartate and inositol, as well as increased levels of glutamine, reflecting the neurologic effects of hyperammonemia [13]
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The mutation of GLP-1 positions 16, 17, 18, and 20 into Ala showed minor effects (IC 50 from 0.27 nM to 1.7, 0.46, 0.68, and 1.7 nM
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