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Chemotherapy-induced peripheral neuropathy Four randomized controlled trials (RCTs) have evaluated the use of acetyl-L-carnitine (LC) for the prevention of chemotherapy-induced peripheral neuropathy (CIPN)
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The protocol was adapted from (Ruhela et al
Safety was similar in resmetirom and placebo arm [10]
GSK-3 inhibition is also involved in Schwann cell differentiation and myelination (Tsukamoto et al., 2015) and proliferation of Schwann cells (Tan et al., 2018)
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