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Patients with long-standing alcohol use, restrictive diets, malabsorption syndromes, or prolonged use of medications that deplete or interfere with B vitamins may particularly benefit when a deficiency is confirmed
This is especially true in the world of injectable or IV glutathione
Whilst in conventional medical practice B12 deficiency is generally treated with intramuscular injections, it is generally accepted that oral (per os) administration at a high dose is as effective at improving B12 status
The pentose phosphate pathway in relation to glycolysis, glycogen metabolism and the tricarboxylic acid (TCA) cycle (Litwack et al., 2018) Linking the Pentose Phosphate Pathway and Glutathione Metabolism One fascinating aspect of the pentose phosphate pathway is its direct involvement in the production of NADPH, which plays a crucial role in maintaining cellular redox balance