Its a sister peptide to GHK-Cu with a nearly identical size and chemistry, but a somewhat different receptor binding profile that makes it more selective for hair follicle stimulation than GHK-Cu
In the treatment of children with an inborn error in the production of transcobalamin II, the binding protein that transports B12 to the cells, serum values are kept at levels of 10 000 pg/ml (about 7 400 pmol/L) without any side-effects
This configuration supports receptor-level interaction within adipocytes while minimizing affinity for the growth hormone receptor, distinguishing it from full-length GH and preventing downstream IGF-1 pathway activation
That can feel unsettling
During this time, in vitro, in vivo, and in silico studies on this tetrapeptide have been performed, supporting the geroprotective and neuroendocrine nature of this peptide as result of its antioxidant, neuro-protective, and antimutagenic effects [13]