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Thus, defined essentially by exclusion as a hereditary hemolytic anemia that is not hereditary spherocytosis (or without any other major aberration of red cell morphology), it is not at all surprising that hereditary nonspherocytic hemolytic anemia has proven to be extremely heterogeneous both in etiology and in clinical manifestations
pregnancy must be excluded and effective contraception ensured in women of childbearing potential [16, 60]
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