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Regarding the positive effect of SGLT2 inhibitors on -cell sensitivity to incretin hormones, the combination of incretin-based therapies and SGLT2 inhibitors could be a very effective option for anti-diabetic treatment
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This makes tirzepatide-based medications among the most effective weight loss therapies currently available (Jastreboff et al., NEJM, 2022)
In one preliminary study with mice, Duca and his colleagues found that a fiber in barley, called beta-glucan, induced the most weight loss in obese animals
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