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doi: 10.1056/NEJMoa1411892 93 WaddenTAHollanderPKleinSNiswenderKWooVHalePMet al

Early GLP-1 RAs like exenatide (approved 2005) and liraglutide (2010) were administered as daily injections for type 2 diabetes (T2D)

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Improves Drug Abuse Symptoms: Possibly ameliorates symptoms related to drug abuse and compulsive behaviors

treatment: metformin 1 g/day)