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The effect of DSePA administration on RP was studied by subjecting mice to thoracic irradiation (X- or -rays, 18 Gy), treating them with DSePA (2.5 mg/kg body weight for three time a week for 6 months beginning on the day of irradiation) during the post-irradiation period and monitoring the incidence of RP through immunohistochemical and CT analysis (Table 2) [61, 62]
5.2 Antioxidants for tumors Malignant tumors are severe diseases caused by the uncontrolled and abnormal proliferation of cells
During hypoxia-reperfusion cycles, ROS production increases, overwhelming the antioxidant defense system and promoting ferroptosis in trophoblast cells (Figure 1
However, we found that four genes, IL-1, IL8, HSPA1A and FOSL1, were significantly induced by CuCl 2 and Cu(OAc) 2 without inhibiting the cell viability