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Notably, at physiological concentrations, TMAO can enhance the integrity of the bloodbrain barrier through the tight junction regulator annexin A1, limit the reactivity of astrocytes and microglia, and protect the cognitive function of mice from inflammatory challenges

For full technical documentation see the sections above

The timeline for peak results in these tissues is 4 to 6 months of consistent protocol adherence, not the 4-week improvements some internet resources suggest

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Adems, el mantener las reservas de glucgeno activas, evita que se queme el msculo durante el ejercicio