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The lactylation of K62 on pyruvate kinase M2 (PKM2), a crucial enzyme in glycolysis, inhibits its transition from tetramer to dimer and enhances its pyruvate kinase activity, thereby suppressing inflammatory metabolic adaptation in pro-inflammatory macrophages
Main Ingredients: Glutathione, SPF 45
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Additionally, it suppresses the production of pro-inflammatory cytokines (like IL-6 and TNF-), creating a favorable, low-inflammation environment that accelerates the healing cascade and protects tissues from oxidative stress
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