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With the accumulation of related studies, current evidence has been concentrated mainly in diseases that have been more extensively investigated, such as SLE, RA, IBD, and MS
(By the way, this is precisely what makes HILIC an orthogonal technique to RPLC!) By contrast, retention in many HILIC columns depends on the semi-immobilized water layer formed at the interface of the polar stationary phase and the organic-rich mobile phase
Efficacy and safety of once-weekly semaglutide 20 mg versus 10 mg in patients with type 2 diabetes (SUSTAIN FORTE): a double-blind, randomised, phase 3B trial
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