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Drug safety testing involved analyzing serum biochemical markers (CK, CKMB, ALT, AST, CREA, BUN) to evaluate potential adverse effects on myocardial, liver, and renal function in treated mice [2]
5-Amino-1MQ's effects are most pronounced in tissues with elevated NNMT activity, which correlates strongly with obesity and insulin resistance
HUBERMAN: The logic is all there, but the pieces are sort of clued together between what we know about the animal studies, what we know about the naturally occurring compounds that these peptides are designed to mimic