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Active GLP-1 levels were determined by using an active GLP-1 ELISA kit (EGLP-35K, Merck/millipore) according to the manufacturers instructions
Data were analysed using one-way ANOVA with Bonferroni post hoc multiple-comparison test ( d , e , h ), two-way repeated-measures ANOVA ( a , c , f , g ), or Kruskall-Wallis test with uncorrected Dunnss test ( i )
By removing the psychological and practical barriers associated with injectable treatments, oral GLP-1s have the potential to reposition obesity care as a routine, chronic intervention rather than a specialist-led, escalation therapy
It is essential to emphasise that any use of GLP-1 medications in Hashimoto's patients would be off-label unless the individual also meets criteria for type 2 diabetes or obesity treatment according to the medication's SmPC
