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[33] broadened the scope to 26 studies ( n = 3,020), including both metabolic RCTs with secondary psychiatric outcomes and a small number of trials in clinical populations (e.g., substance use disorders)
Cardiovascular risk reduction: Approved for adults with established cardiovascular disease who are also overweight or obese
doi: 10.1016/j.seizure.2024.08.003 24 SchwartzRHEatonJBowerBDAynsley-GreenA
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In early Phase 2 trials, participants lost up to approximately 24% of their body weight over 48 weeks at higher doses
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