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Supplementary Data 3 (download XLSX Source data for Supplementary Fig
Importantly, steatosis does not seem to cause a parallel resistance to the hyperglycaemic effects of glucagon (with glycogenolysis taking place mainly in the central part of the liver acinus and amino acid metabolism taking part in the portal end), so hyperglucagonaemia still contributes to diabetes-associated hyperglycaemia [42, 43]
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