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Because the weight loss process on GLP-1s is so fast, she said people need to be extra vigilant in their nutritional intake, specifically increasing their intake of protein, to avoid sarcopenic obesity

13,14 This reduction in MACE, which is not explained by improvements in glycaemia and nonglycaemic cardiovascular risk factors, remains to be fully elucidated but may reflect other effects of GLP-1 analogues such as their antioxidative and anti-inflammatory properties

This is consistent with crypt hyperplasia and expansion of the transit-amplifying zone, both histologic hallmarks of inflammation

However, coverage for weight-loss-specific brands like Wegovy, Zepbound or Saxenda is not guaranteed and is often not included