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To do so, we could tailor these nanostructures to have an optimal therapeutic effect both in the metabolic disorders and directly in the liver if a sufficient amount can reach the liver after oral administration

Identity by mass spec is straightforward, but copper content needs to be quantified too, and a clean batch will have both

Drawing to the "25" line on a U-40 syringe gives you 0.625 mL instead of the 0.25 mL you expected, a 2.5x overdose

2B) to the point where a dose-response curve and half-maximal effective concentration (EC 50 ) could be defined