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Collectively, this study identifies GGCT as a metabolic switch that diverts Gln flux toward GSH synthesis to maintain redox homeostasis, while enhancing glucose-fueled anaplerosis into the TCA cycle to sustain cell proliferation
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In addition, mRNA abundance was decreased in polycystic ovary syndrome in rat, suggesting OS [76]
GLP-1 drugs, including Zepbound for weight loss , rely on steady hormone levels in the body to maintain appetite control
The oxidative pathway produces N-acetyl-p-benzoquinone imine (NAPQI), a highly reactive metabolite capable of binding cellular proteins and causing hepatocyte death
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