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The medication works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in response to food intake, suppresses glucagon release, and slows gastric emptying

That food noise does come back if you come off the medicine, Neal said

STEP HFpEF is the first randomized clinical trial to show that intentional weight loss (via semaglutide) results in significant improvement in clinical status for patients with heart failure and preserved ejection fraction

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