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Neither compound has published the kind of long-term hard-outcome data (cardiovascular events, mortality) that ultimately defines a metabolic drugs value, because both are too early in development for that

Ibuprofen is an NSAID that may irritate the stomach lining and increase risk of gastric ulceration, particularly with prolonged use

It is a treatment that works only while it is being used

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Rachele cautions, There is a strict contraindication for pregnancy