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Mechanistically, GAS5 inhibits proliferation and promotes apoptosis through the regulation of E2F1, p21, and p53, and suppresses oncogenic pathways including EGFR, MAPK, and AKT
Side effects are usually mild and temporary
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Some patients find relief by taking the injection at a different time of day or by ensuring the medication has reached room temperature before injection
References 1 SmolenJSAletahaDBartonABurmesterGREmeryPFiresteinGSet al
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